Table 3 Inhibition of Platelet aggregation (PA) in human:
From: Effect of garlic on cardiovascular disorders: a review
References | Preparations | Duration | Effect |
|---|---|---|---|
Bordia, 1978 [72] | Garlic | In-vitro | Dose-dependent Platelet aggregation |
Vanderhock et al., 1980 [73] | Garlic oil | In vitro | Inhibit PA |
Boullin, 1981 [80] | Fresh garlic | Single Dose | Inhibit PA |
Ariga et al., 1981 [85] | Methyl allyl trisulfide | In vitro | Inhibit PA |
Arora and Arora, 1981 [54] | Ether extract of garlic | Single Dose | Increased coagulation time |
Bordia et al., 1982 [51] | Ether extract of garlic | 3 weeks | Inhibit PA |
Samson, 1982 [76] | Essential garlic oil | 10 days | No PA activity |
Apitz-Castro et al., 1983 [74] | Garlic extract and 3 pure component | In vitro | Inhibit PA |
Block et al., 1984 [86] | Ajoene | In vitro | Inhibit PA |
Srivastava, 1984 [61] | Aqueous extract of garlic | In vitro | Inhibit PA |
Srivastava, 1986 [75] | Aqueous extract of garlic | In vitro | Inhibit PA |
Harenberg et al., 1988 [77] | Dried garlic powder | 4 weeks | No PA activity |
Kiesewetter et al., 1991 [78] | Garlic powder | 4 weeks | Inhibit PA |
Kiesewetter et al., 1993 [87] | Garlic powder | 4 weeks | Inhibit PA |
Legnani et al., 1993 [56] | Garlic powder | Single Dose and 14 days | Inhibit PA |
Morris et al., 1995 [88] | Oil extract (equivalent to 15 gm of raw garlic) | In-vitro and in-vivo (5 days) | Inhibit PA in in-vitro No in-vivo PA activity |
Bordia et al., 1998 [57] | Ethyl acetate extract of garlic | In-vitro study | Inhibit PA |
Sreiner and Lin, 1998 [79] | Aged garlic extract | 10 months | Inhibit PA |
Rahman and Billington, 2000 [28] | Aged garlic extract | 13 weeks | Inhibit PA |
Steiner and Li, 2001 [89] | Aged garlic extract | 6 weeks | Dose dependent inhibition of PA |