Table 4 Hazard ratios (95% CI) of CVD events by individual choline forms tertile
Individual choline forms | Tertile 1 | Tertile 2 | Tertile 3 | P trend | Continuous | P trend |
|---|---|---|---|---|---|---|
Free choline (FC) | ||||||
Median (mg/d) | 45.8 | 57.6 | 71.4 | Per 10 mg/d | ||
Age and sex-adjusted model | 1 | 0.79 (0.55–1.14) | 0.82 (0.58–1.68) | 0.34 | 0.96 (0.88–1.05) | 0.44 |
aMultivariate-adjusted model | 1 | 0.79 (0.54–1.16) | 0.64 (0.42–0.98) | 0.04 | 0.90 (0.80–1.01) | 0.08 |
Glycerophosphocholine (GPC) | ||||||
Median (mg/d) | 30.5 | 43.5 | 59.5 | Per 10 mg/d | ||
Age and sex-adjusted model | 1 | 0.92 (0.66–1.28) | 0.73 (0.51–1.04) | 0.08 | 0.94 (0.86–1.03) | 0.22 |
aMultivariate-adjusted model | 1 | 0.98 (0.69–1.37) | 0.75 (0.52–1.07) | 0.11 | 0.95 (0.87–1.04) | 0.28 |
Phosphocholine (PC) | ||||||
Median (mg/d) | 7.69 | 11.4 | 15.9 | Per 10 mg/d | ||
Age and sex-adjusted model | 1 | 0.85 (0.60–1.20) | 0.78 (0.55–1.11) | 0.19 | 0.93 (0.84–1.04) | 0.21 |
aMultivariate-adjusted model | 1 | 0.83 (0.57–1.21) | 0.70 (0.46–1.06) | 0.09 | 0.94 (0.83–1.07) | 0.39 |
Phosphatidylcholine (PtC) | ||||||
Median (mg/d) | 67.7 | 95.8 | 138 | Per 10 mg/d | ||
Age and sex-adjusted model | 1 | 1.05 (0.76–1.45) | 0.84 (0.58–1.21) | 0.33 | 0.98 (0.95–1.01) | 0.35 |
aMultivariate-adjusted model | 1 | 1.13 (0.79–1.61) | 0.95 (0.60–1.50) | 0.81 | 1.00 (0.95–1.05) | 0.84 |
Sphingomyelin (SM) | ||||||
Median (mg/d) | 6.90 | 9.88 | 14.0 | Per 10 mg/d | ||
Age and sex-adjusted model | 1 | 1.08 (0.78–1.48) | 0.70 (0.48–1.01) | 0.06 | 0.69 (0.49–0.98) | 0.04 |
aMultivariate-adjusted model | 1 | 1.19 (0.84–1.68) | 0.72 (0.47–1.13) | 0.16 | 0.76 (0.49–1.19) | 0.24 |