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Table 2 Association between fish oil use and risk of SLE among the 390,277 participants

From: Fish oil supplementation and risk of incident systemic lupus erythematosus: a large population-based prospective study

 

Fish oil non-users (n = 267,448)

Fish oil users (n = 122,829)

p-value

Number of cases

141

68

 

Person-years

3,092,936

1,423,781

 

HR (95% CI)

   

Model 1

1 (ref)

0.94 (0.70, 1.27)

0.70

Model 2

1 (ref)

0.84 (0.61, 1.15)

0.28

Model 3

1 (ref)

0.86 (0.63, 1.18)

0.36

Model 4

1 (ref)

0.85 (0.62, 1.16)

0.30

  1. CI, confidence interval; HR, hazard ratio
  2. Model 1 adjusted for age and sex; Model 2 adjusted for age, sex, race, location of assessment centers, BMI, education, Townsend deprivation index, smoking status, alcohol drinking status, physical activity, vitamin supplementation use, mineral supplementation use, nonsteroidal anti-inflammatory drugs use, history of hypertension, history of diabetes, history of hyperlipemia and ultraviolet radiation; Model 3 further adjusted for fruits, vegetables, whole grains, refined grains, fish, dairy products, vegetable oil, processed meat, unprocessed meat, and sugar-sweetened beverages based on model 2; Model 4 further adjusted for healthy diet score based on model 2