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Fig. 1 | Nutrition Journal

Fig. 1

From: Relationship between sex, APOE genotype, endocannabinoids and cognitive change in older adults with metabolic syndrome during a 3-year Mediterranean diet intervention

Fig. 1

Sex and gender differences in baseline cognitive performance (A, C, E) and in cognitive change after 3 years of MedDiet intervention (B, D, F), represented in terms of global cognition (A-B), memory (C-D) and executive functioning (E-F) composites. Each plot consists of two panels: the left panel displays mean values (95%CI), while the right panel depicts modeled differences between men and women. A negative value of the modeled differences (β, 95%CI) indicates an effect favoring men. Gender differences are evaluated using unadjusted (crude) models, while sex differences are tested in models adjusted for gender-related factors (years of education, diabetes, use of tranquilizers or sedatives, use of lipid-lowering agents, baseline MedDiet adherence and baseline physical activity), age and APOE genotype. Bold values denote statistical significance at the p < 0.05 level. Further details are available in Supplementary Tables 1–2

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Nutrition Journal

ISSN: 1475-2891

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