Variables | G1 | G2 | G3 | G4 | G5 | P value |
---|---|---|---|---|---|---|
iP (mmol/L) | < 0.64 | 0.64–0.8 | 0.8–1.16 | 1.16–1.45 | ≥ 1.45 | |
Total, number (%) | 341 (1.5) | 771 (3.3) | 11,479(48.9) | 9,241 (39.4) | 1,647 (7.0) | < 0.001 |
Ren Ji Hospital, number (%) | 302 (1.5) | 657 (3.2) | 9,835 (48.5) | 7,977 (39.4) | 1,489 (7.3) | < 0.001 |
Xin Hua Hospital, number (%) | 39 (1.2) | 114 (3.5) | 1,644 (51.1) | 1,264 (39.3) | 158 (4.9) | |
Age, y | 62.1 ± 17.3 | 61.7 ± 18.0 | 60.0 ± 16.6 | 55.8 ± 16.6 | 49.2 ± 16.9 | < 0.001 |
Sex, male, % | 62.2 | 74.3 | 67.3 | 51 | 51.7 | < 0.001 |
BMI, kg/m2 | 23.3 ± 3.7 | 23.0 ± 3.8 | 23.4 ± 3.7 | 23.5 ± 3.7 | 23.4 ± 3.7 | 0.006 |
CCI, point | 2 (0, 2) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | < 0.001 |
CCI, 0 point, % | 36.9 | 40.6 | 48.7 | 38.6 | 41.2 | < 0.001 |
CCI, 1–2 points, % | 46.4 | 45.1 | 48.4 | 49.8 | 47.8 | |
CCI ≥ 3 points, % | 16.6 | 14.3 | 12.3 | 11.6 | 11.0 | |
Surgery, yes, % | 58.9 | 49.0 | 46.3 | 46.4 | 49.6 | < 0.001 |
Mortality, % | 5.3 | 1.9 | 0.4 | 0.3 | 0.5 | < 0.001 |
LOS, day | 12, (8, 20) | 8, (6, 14) | 7, (4, 10) | 6, (4, 9) | 7, (5, 10) | < 0.001 |
Phosphate, mmol/L | 0.52 (0.40, 0.58) | 0.74 (0.70, 0.77) | 1.03 (0.95, 1.10) | 1.26 (1.17, 1.32) | 1.54 (1.49, 1.65) | < 0.001 |
Calcium, mmol/L | 2.12 (2.00, 2.24) | 2.18 (2.12, 2.27) | 2.21 (2.15, 2.28) | 2.23 (2.17, 2.30) | 2.25 (2.18, 2.33) | < 0.001 |
Magnesium, mmol/L | 0.84 ± 0.14 | 0.88 ± 0.10 | 0.89 ± 0.09 | 0.90 ± 0.09 | 0.91 ± 0.10 | < 0.001 |
Sodium, mmol/L | 138.7 ± 5.0 | 139.7 ± 4.2 | 140.6 ± 3.2 | 140.7 ± 3.3 | 140.7 ± 3.3 | < 0.001 |
Potassium, mmol/L | 3.5 ± 0.6 | 3.4 ± 0.5 | 3.5 ± 0.4 | 3.6 ± 0.4 | 3.6 ± 0.5 | < 0.001 |
Chloride, mmol/L | 102.8 ± 4.8 | 103.3 ± 4.5 | 103.5 ± 4.1 | 103.3 ± 4.6 | 102.0 ± 5.1 | < 0.001 |
eGFR-EPI, ml/min/1.73m2 | 97.6 ± 24.9 | 94.4 ± 26.1 | 94.9 ± 24.8 | 97.3 ± 25.4 | 101.6 ± 27.7 | < 0.001 |
25(OH)D, ng/ml | 13.6 (7.6, 18.4) | 16.2 (11.1, 23.2) | 17.2 (12.3, 23.0) | 16.2 (11.6, 21.8) | 15.2 (10.8, 20.4) | < 0.001 |
Vitamin D2, ng/ml | 0.5 (0.5, 0.9) | 0.5 (0.5, 0.7) | 0.5 (0.5, 0.8) | 0.5 (0.5, 0.8) | 0.5 (0.5, 0.7) | < 0.001 |
Vitamin D3, ng/ml | 9.0 (5.9, 14.6) | 13.4 (8.2, 19.2) | 15.3 (10.6, 20.8) | 15.1 (10.6, 20.4) | 14.7 (10.2, 20.3) | < 0.001 |
Albumin, g/L | 35.4 ± 6.6 | 37.7 ± 6.3 | 39.7 ± 5.8 | 40.0 ± 6.0 | 40.0 ± 6.7 | < 0.001 |
Pre-albumin, mg/L | 159.8 ± 73.5 | 192 ± 72.4 | 221.0 ± 60.5 | 231.3 ± 58.2 | 231.6 ± 64.7 | < 0.001 |
Hemoglobin, g/L | 110.5 ± 31.1 | 123.6 ± 26.6 | 130.0 ± 21.9 | 128.7 ± 20.9 | 125.3 ± 25.0 | < 0.001 |
ALT, U/L | 17, (11, 28) | 17, (12, 27) | 17, (12, 26) | 17, (12, 26) | 18, (12, 28) | 0.175 |
AST, U/L | 21, (16, 31) | 21, (16, 29) | 19, (15, 26) | 19, (15, 26) | 19, (15, 27) | < 0.001 |
ALP, U/L | 75 (61, 99) | 77 (64, 96) | 75 (61, 91) | 74 (60, 90) | 73 (60, 90) | < 0.001 |
γ-GT, U/L | 26, (15, 51) | 23, (16, 43) | 23, (16, 36) | 23, (15, 37) | 23, (16, 40) | 0.003 |
TBIL, mmol/L | 10.8 (7.2, 18.1) | 11.0 (7.8, 15.7) | 10.4 (7.6, 14.2) | 9.6 (7.0, 13.1) | 8.8 (6.3, 12.2) | < 0.001 |
DBIL, mmol/L | 3.8 (2.6, 6.4) | 3.6 (2.4, 5.3) | 3.2 (2.2, 4.5) | 2.9 (2.0, 4.0) | 2.7 (1.9, 3.8) | < 0.001 |
TC, mmol/L | 3.53 (2.65, 4.48) | 3.93 (3.25, 4.79) | 4.23 (3.54, 5.02) | 4.46 (3.69, 5.28) | 4.40 (3.70, 5.33) | < 0.001 |
TG, mmol/L | 1.16 (0.83, 1.72) | 1.24 (0.88, 1.78) | 1.30 (0.93, 1.85) | 1.38 (0.97, 2.02) | 1.41 (0.97, 2.19) | < 0.001 |
FBG, mmol/L | 5.7 (4.8, 7.6) | 5.5 (4.8, 7.0) | 5.4 (4.7, 6.9) | 5.3 (4.6, 6.7) | 5.2 (4.4, 6.5) | < 0.001 |
WBC, 109/L | 6.7 (4.6, 9.3) | 6.2 (5, 8.1) | 6.0 (4.9, 7.4) | 6.1 (5.0, 7.5) | 6.3 (4.9, 7.8) | < 0.001 |