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Table 1 Baseline characteristics of 23,479 Chinese adult inpatients included

From: The association between serum phosphate and length of hospital stay and all-cause mortality in adult patients: a cross-sectional study

Variables

G1

G2

G3

G4

G5

P value

iP (mmol/L)

< 0.64

0.64–0.8

0.8–1.16

1.16–1.45

≥ 1.45

 

Total, number (%)

341 (1.5)

771 (3.3)

11,479(48.9)

9,241 (39.4)

1,647 (7.0)

< 0.001

Ren Ji Hospital, number (%)

302 (1.5)

657 (3.2)

9,835 (48.5)

7,977 (39.4)

1,489 (7.3)

< 0.001

Xin Hua Hospital, number (%)

39 (1.2)

114 (3.5)

1,644 (51.1)

1,264 (39.3)

158 (4.9)

 

Age, y

62.1 ± 17.3

61.7 ± 18.0

60.0 ± 16.6

55.8 ± 16.6

49.2 ± 16.9

< 0.001

Sex, male, %

62.2

74.3

67.3

51

51.7

< 0.001

BMI, kg/m2

23.3 ± 3.7

23.0 ± 3.8

23.4 ± 3.7

23.5 ± 3.7

23.4 ± 3.7

0.006

CCI, point

2 (0, 2)

1 (0, 2)

1 (0, 2)

1 (0, 2)

1 (0, 2)

< 0.001

CCI, 0 point, %

36.9

40.6

48.7

38.6

41.2

< 0.001

CCI, 1–2 points, %

46.4

45.1

48.4

49.8

47.8

 

CCI ≥ 3 points, %

16.6

14.3

12.3

11.6

11.0

 

Surgery, yes, %

58.9

49.0

46.3

46.4

49.6

< 0.001

Mortality, %

5.3

1.9

0.4

0.3

0.5

< 0.001

LOS, day

12, (8, 20)

8, (6, 14)

7, (4, 10)

6, (4, 9)

7, (5, 10)

< 0.001

Phosphate, mmol/L

0.52 (0.40, 0.58)

0.74 (0.70, 0.77)

1.03 (0.95, 1.10)

1.26 (1.17, 1.32)

1.54 (1.49, 1.65)

< 0.001

Calcium, mmol/L

2.12 (2.00, 2.24)

2.18 (2.12, 2.27)

2.21 (2.15, 2.28)

2.23 (2.17, 2.30)

2.25 (2.18, 2.33)

< 0.001

Magnesium, mmol/L

0.84 ± 0.14

0.88 ± 0.10

0.89 ± 0.09

0.90 ± 0.09

0.91 ± 0.10

< 0.001

Sodium, mmol/L

138.7 ± 5.0

139.7 ± 4.2

140.6 ± 3.2

140.7 ± 3.3

140.7 ± 3.3

< 0.001

Potassium, mmol/L

3.5 ± 0.6

3.4 ± 0.5

3.5 ± 0.4

3.6 ± 0.4

3.6 ± 0.5

< 0.001

Chloride, mmol/L

102.8 ± 4.8

103.3 ± 4.5

103.5 ± 4.1

103.3 ± 4.6

102.0 ± 5.1

< 0.001

eGFR-EPI, ml/min/1.73m2

97.6 ± 24.9

94.4 ± 26.1

94.9 ± 24.8

97.3 ± 25.4

101.6 ± 27.7

< 0.001

25(OH)D, ng/ml

13.6 (7.6, 18.4)

16.2 (11.1, 23.2)

17.2 (12.3, 23.0)

16.2 (11.6, 21.8)

15.2 (10.8, 20.4)

< 0.001

Vitamin D2, ng/ml

0.5 (0.5, 0.9)

0.5 (0.5, 0.7)

0.5 (0.5, 0.8)

0.5 (0.5, 0.8)

0.5 (0.5, 0.7)

< 0.001

Vitamin D3, ng/ml

9.0 (5.9, 14.6)

13.4 (8.2, 19.2)

15.3 (10.6, 20.8)

15.1 (10.6, 20.4)

14.7 (10.2, 20.3)

< 0.001

Albumin, g/L

35.4 ± 6.6

37.7 ± 6.3

39.7 ± 5.8

40.0 ± 6.0

40.0 ± 6.7

< 0.001

Pre-albumin, mg/L

159.8 ± 73.5

192 ± 72.4

221.0 ± 60.5

231.3 ± 58.2

231.6 ± 64.7

< 0.001

Hemoglobin, g/L

110.5 ± 31.1

123.6 ± 26.6

130.0 ± 21.9

128.7 ± 20.9

125.3 ± 25.0

< 0.001

ALT, U/L

17, (11, 28)

17, (12, 27)

17, (12, 26)

17, (12, 26)

18, (12, 28)

0.175

AST, U/L

21, (16, 31)

21, (16, 29)

19, (15, 26)

19, (15, 26)

19, (15, 27)

< 0.001

ALP, U/L

75 (61, 99)

77 (64, 96)

75 (61, 91)

74 (60, 90)

73 (60, 90)

< 0.001

γ-GT, U/L

26, (15, 51)

23, (16, 43)

23, (16, 36)

23, (15, 37)

23, (16, 40)

0.003

TBIL, mmol/L

10.8 (7.2, 18.1)

11.0 (7.8, 15.7)

10.4 (7.6, 14.2)

9.6 (7.0, 13.1)

8.8 (6.3, 12.2)

< 0.001

DBIL, mmol/L

3.8 (2.6, 6.4)

3.6 (2.4, 5.3)

3.2 (2.2, 4.5)

2.9 (2.0, 4.0)

2.7 (1.9, 3.8)

< 0.001

TC, mmol/L

3.53 (2.65, 4.48)

3.93 (3.25, 4.79)

4.23 (3.54, 5.02)

4.46 (3.69, 5.28)

4.40 (3.70, 5.33)

< 0.001

TG, mmol/L

1.16 (0.83, 1.72)

1.24 (0.88, 1.78)

1.30 (0.93, 1.85)

1.38 (0.97, 2.02)

1.41 (0.97, 2.19)

< 0.001

FBG, mmol/L

5.7 (4.8, 7.6)

5.5 (4.8, 7.0)

5.4 (4.7, 6.9)

5.3 (4.6, 6.7)

5.2 (4.4, 6.5)

< 0.001

WBC, 109/L

6.7 (4.6, 9.3)

6.2 (5, 8.1)

6.0 (4.9, 7.4)

6.1 (5.0, 7.5)

6.3 (4.9, 7.8)

< 0.001

  1. Note:
  2. 1. Abbreviation: iP, inorganic phosphorus; BMI, body mass index; CCI, Charlson Comorbidity index; LOS, length of hospital stay; eGFR-EPI, estimated glomerular filtration rate calculated by Chronic Kidney Disease Epidemiology Collaboration equation; ALT, alanine transferase; AST, aspartate aminotransferase; AKP, alkaline phosphatase; γ-GT, gamma glutamyl-transferase; WBC, white blood cell; FBG, fasting blood glucose; HIV, human immunodeficiency virus; AIDS, acquired immune deficiency syndrome; 25(OH)D, 25 hydroxyvitamin D; Vitamin D2, 25 hydroxyvitamin D2; Vitamin D3, 25 hydroxyvitamin D3; TBIL, total bilirubin; DBIL, direct bilirubin; TC, total cholesterol; TG, triglycerides
  3. 2. Abnormal distribution data were shown as median and quartile range
  4. 3. CCI without terms of HIV infection and AIDS was used to assess the disease severity
  5. 4. LOS was defined as the time between the measurement of serum phosphate and discharge time or the time of death
  6. 5. Serum calcium (mmol/L) was calculated as the following equation: serum total calcium (mmol/L) + 0.8×[40-serum albumin (g/L)]