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Table 1 Characteristics of participants

From: Very high high-density lipoprotein cholesterol may be associated with higher risk of cognitive impairment in older adults

Characteristics

HDL-C level (mmol/L)

< 1.00

1.00-1.49

1.50–1.99

2.00-2.49

≥ 2.50

Toll participants

518

1850

941

263

60

Sex, n (%)

     

 Male

382 (73.7)

967 (52.3)

321 (34.1)

71 (27.0)

19 (31.7)

 Female

136 (26.3)

883 (47.7)

620 (65.9)

192 (73.0)

41 (68.3)

Age, n (%)

     

 60–69 years

269 (51.9)

959 (51.8)

460 (48.9)

132 (50.2)

28 (46.7)

 70–79 years

164 (31.7)

542 (29.3)

261 (27.7)

77 (29.3)

25 (41.7)

 ≥ 80 years

85 (16.4)

349 (18.9)

220 (23.4)

54 (20.5)

7 (11.7)

Race, n (%)

     

 Mexican American

53 (10.2)

198 (10.7)

73 (7.8)

9 (3.4)

3 (5.0)

 Other Hispanic

57 (11.0)

228 (12.3)

73 (7.8)

10 (3.8)

0 (0.0)

 Non-Hispanic White

256 (49.4)

794 (42.9)

430 (45.7)

141 (53.6)

27 (45.0)

 Non-Hispanic Black

97 (18.7)

428 (23.1)

249 (24.5)

69 (26.2)

28 (46.7)

 Other race

55 (10.6)

202 (10.9)

116 (12.3)

34 (12.9)

2 (3.3)

BMI, n (%)

     

 <25 kg/m2

69 (13.3)

420 (22.7)

341 (36.2)

147 (55.9)

29 (48.3)

 25 to < 30 kg/m2

207 (40.0)

655 (35.4)

316 (33.6)

70 (26.6)

23 (38.3)

 ≥ 30 kg/m2

242 (46.7)

775 (41.9)

284 (30.2)

46 (17.5)

8 (13.3)

Educational level, n (%)

     

 Less than high school

179 (34.6)

577 (31.2)

258 (27.4)

54 (20.5)

8 (13.3)

 High school

136 (26.3)

428 (23.1)

206 (21.9)

54 (20.5)

15 (25.0)

 College or higher

203 (39.2)

845 (45.7)

477 (50.7)

155 (58.9)

37 (61.7)

Physical activity, n (%)

     

 Low intensity

284 (54.8)

1009 (54.5)

477 (50.7)

115 (43.7)

23 (38.3)

 High intensity

234 (45.2)

841 (45.5)

464 (49.3)

148 (56.3)

37 (61.7)

Hypertension, n (%)

     

 Yes

352 (68.0)

1191 (64.4)

582 (61.8)

132 (50.2)

34 (56.7)

 No

166 (32.0)

659 (35.6)

359 (38.2)

131 (49.8)

26 (43.3)

Diabetes, n (%)

     

 Yes

189 (36.5)

510 (27.6)

145 (15.4)

23 (8.7)

6 (10.0)

 No

329 (63.5)

1340 (72.4)

796 (84.6)

240 (91.3)

54 (90.0)

Smoking, n (%)

     

 Current

94 (18.1)

230 (12.4)

93 (9.9)

36 (13.7)

12 (20.0)

 Never

213 (41.1)

911 (49.2)

530 (56.3)

131 (49.8)

32 (53.3)

 Former

211 (40.7)

709 (38.3)

318 (33.8)

96 (36.5)

16 (26.7)

Alcohol consumption, n (%)

     

 Yes

349 (67.4)

1155 (62.4)

586 (62.3)

182 (69.2)

53 (88.3)

 No

169 (32.6)

695 (37.6)

355 (37.7)

81 (30.8)

7 (11.7)

Lipid-lowering therapy, n (%)

     

 Yes

431 (83.2)

1542 (83.4)

789 (83.8)

214 (81.4)

46 (76.7)

 No

87 (16.8)

308 (16.6)

152 (16.2)

49 (18.6)

14 (23.3)

HDL-C (mmol/L)

33.4 (3.9)

47.9 (5.3)

65.7 (5.3)

83.9 (5.2)

110.7 (16.4)

LDL-C (mmol/L)

97.8 (32.5)

104.2 (35.0)

103.8 (35.2)

101.0 (32.6)

101.1 (32.6)

TG (mmol/L)

206.5 (148.6)

173.4 (135.0)

145.9 (129.3)

135.6 (130.9)

103.8 (95.5)

Cognitive impairment, n (%)

     

 Yes

161 (31.1)

464 (25.1)

219 (23.3)

45 (17.1)

17 (28.3)

 No

357 (68.9)

1386 (74.9)

722 (76.7)

218 (82.9)

43 (71.7)

  1. BMI: body mass index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglyceride