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Table 2 Primary and secondary outcome parameters

From: Early intravenous branched-chain amino acid-enriched nutrition supplementation in older patients undergoing gastric surgery: a randomized clinical trial

Outcomes

HBCAA group (n = 70)

Control group (n = 67)

Mean/risk difference (95% CI)

P

Primary outcome

 Standard LOS, d

8 (7.5, 8)

8.5 (8, 9)

0.38 (0.02 to 0.74)

 < .001

Secondary outcomes

 Postop. First flatus, d

3 (2.5, 3.5)

3 (3, 4)

0.15 (-0.12 to 0.42)

.179

 Postop. First defecation, d

4 (3.6, 5)

5 (4, 5.5)

0.60 (0.26 to 0.94)

 < .001

 PONV, n (%)

1 (1.43)

2 (2.99)

1.56 (-3.38 to 6.49)

.969

 Postop. Liquid diet, d

5 (5, 6)

5 (5, 6)

-0.05 (-0.40 to 0.29)

.834

 Postop. Semi-liquid diet, d

8 (7.5, 8)

8 (8, 8.75)

0.36 (0.03 to 0.70)

 < .001

 Gastrointestinal tube removal, d

2 (1, 3)

2 (1, 4)

0.28 (-0.18 to 0.74)

.251

 Ureter tube removal, d

4 (4, 4)

4 (4, 4)

0.159 (-0.10 to 0.42)

.437

 Postop. Ambulation, d

2 (2, 2)

2 (2, 2.75)

0.08 (-0.11 to 0.27)

.633

 Weight loss, %

3.5 (2.7, 6.5)

4.9 (3.3, 7.6)

1.23 (0.27 to 2.19)

.011

 Major complications, n (%)

15 (21.43)

10 (14.93)

-6.5 (-19.36 to 6.35)

.445

 Hospitalization costs, mean (SD), ¥

58,733.6 (9517.7)

57,475.3 (8274.4)

2942.41 (-2570.12 to 7095.87)

.253

 28-day mortality, n (%)

NA

NA

  

 28-day readmission, n (%)

1 (1.43)

3 (4.48)

3.05 (-2.63 to 8.73)

.581

  1. Data are presented as median (IQR) unless otherwise indicated, with the P-value representing the significance level for differences between the HBCAA and control group (Student’s t-test, the Mann–Whitney U test, Pearson’s χ2 test, or Fisher’s exact test)
  2. Abbreviations: HBCAA High-proportion branched-chain amino acids, CI Confidence interval, LOS Length of hospital stay, Postop Postoperative, PONV Postoperative nausea and vomiting, SD Standard deviation, IQR Interquartile range