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Table 2 Association between total flavonoid, six flavonoid subclasses and PhenoAgeAccel

From: Dietary flavonoid intake is negatively associated with accelerating aging: an American population-based cross-sectional study

Variable

Model 1

Model 2

Model 3

 

β (95% CI)

β (95% CI)

β (95% CI)

Isoflavones

Q1

Reference

Reference

Reference

Q2

-0.26 (-1.20, 0.68)

0.32 (-0.59, 1.23)

-0.27 (-1.34, 0.79)

Q3

-1.00 (-1.89, -0.11)

-0.54 (-1.35, 0.26)

-0.49 (-1.19, 0.21)

Q4

-0.87 (-1.84, 0.11)

-0.52 (-1.42, 0.38)

-0.73 (-1.49, 0.03)

Q5

-1.55 (-2.46, -0.63)

-0.9 (-1.80, -0.00)

-0.51 (-1.17, 0.15)

P for trend

< 0.001

0.020

0.049

Anthocyanidins

Q1

Reference

Reference

Reference

Q2

-0.37 (-1.22, 0.48)

-0.33 (-1.16, 0.51)

-0.27 (-1.34, 0.79)

Q3

-1.42 (-2.44, -0.40)

-1.58 (-2.56, -0.61)

-0.49 (-1.19, 0.21)

Q4

-1.82 (-2.64, -1.01)

-1.74 (-2.42, -1.06)

-0.73 (-1.49, 0.03)

Q5

-2.00 (-3.00, -1.00)

-1.52 (-2.42, -0.61)

-0.51 (-1.17, 0.15)

P for trend

< 0.001

< 0.001

0.049

Flavan-3-ols

Q1

Reference

Reference

Reference

Q2

-1.57 (-2.30, -0.83)

-1.47 (-2.25, -0.69)

-0.95 (-1.61, -0.30)

Q3

-2.06 (-2.95, -1.18)

-1.90 (-2.73, -1.08)

-1.05 (-1.79, -0.31)

Q4

-1.62 (-2.57, -0.68)

-1.23 (-2.14, -0.32)

0.08 (-0.78, 0.94)

Q5

-1.90 (-2.68, -1.12)

-1.34 (-2.06, -0.63)

-0.83 (-1.59, -0.08)

P for trend

< 0.001

0.007

0.473

Flavanones

Q1

Reference

Reference

Reference

Q2

-0.97 (-1.88, -0.06)

-0.44 (-1.41, 0.52)

-0.05 (-0.85, 0.75)

Q3

-2.17 (-3.02, -1.31)

-1.58 (-2.46, -0.70)

-1.14 (-1.90, -0.38)

Q4

-2.71 (-3.65, -1.77)

-2.32 (-3.29, -1.34)

-1.18 (-1.98, -0.39)

Q5

-1.55 (-2.59, -0.51)

-1.66 (-2.68, -0.63)

-0.57 (-1.43, 0.28)

P for trend

< 0.001

< 0.001

0.016

Flavones

Q1

Reference

Reference

Reference

Q2

-0.66 (-1.61, 0.30)

-0.61 (-1.52, 0.31)

-0.73 (-1.56, 0.10)

Q3

-2.36 (-3.10, -1.62)

-2.08 (-2.81, -1.35)

-1.75 (-2.56, -0.95)

Q4

-2.89 (-3.97, -1.80)

-2.5 (-3.59, -1.41)

-1.83 (-2.83, -0.84)

Q5

-2.69 (-3.63, -1.74)

-2.27 (-3.22, -1.31)

-1.64 (-2.52, -0.77)

P for trend

< 0.001

< 0.001

< 0.001

Flavonols

Q1

Reference

Reference

Reference

Q2

-0.94 (-1.91, 0.03)

-0.87 (-1.81, 0.07)

-0.49 (-1.40, 0.43)

Q3

-1.65 (-2.63, -0.67)

-1.47 (-2.35, -0.59)

-0.86 (-1.72, -0.01)

Q4

-2.33 (-3.20, -1.47)

-2.05 (-2.82, -1.28)

-1.20 (-2.01, -0.39)

Q5

-1.92 (-2.76, -1.09)

-1.46 (-2.25, -0.68)

-0.90 (-1.84, 0.04)

 

β (95% CI)

β (95% CI)

β (95% CI)

P for trend

< 0.001

< 0.001

0.032

Total flavonoids

Q1

Reference

Reference

Reference

Q2

-1.61 (-2.49, -0.73)

-1.51 (-2.33, -0.68)

-0.78 (-1.57, 0.01)

Q3

-1.76 (-2.58, -0.94)

-1.89 (-2.68, -1.09)

-0.87 (-1.61, -0.13)

Q4

-1.68 (-2.66, -0.69)

-1.36 (-2.29, -0.42)

-0.07 (-0.92, 0.77)

Q5

-1.81 (-2.63, -0.99)

-1.34 (-2.16, -0.52)

-0.74 (-1.64, 0.15)

P for trend

< 0.001

0.008

0.413

  1. Abbreviations CI, confidence interval; Q1, quintile 1; Q2, quintile 2; Q3, quintile 3; Q4, quintile 4; Q5, quintile 5
  2. Model 1: No adjustments were implemented; Model 2: Adjusted for gender, age, race, poverty income ratio, education level and marital status; Model 3: Adjusted for gender, age, race, poverty income ratio, education level, marital status, drinking, smoking, body mass index, physical activity, diabetes, chronic kidney disease and hypertension
  3. Data in bold type indicate the P values below 0.05