Participants, n | Incidents rate a | Model 1 | Model 2 | Model 3 | ||||
---|---|---|---|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | |||
PDI trajectories | ||||||||
Low and stable | 1438 | 24.3 | Reference | NA | Reference | NA | Reference | NA |
Low and increasing | 859 | 20.4 | 0.86 (0.71, 1.03) | 0.10 | 0.90 (0.75, 1.09) | 0.27 | 0.92 (0.76, 1.12) | 0.42 |
High and decreasing | 556 | 22.3 | 0.84 (0.68, 1.03) | 0.10 | 0.80 (0.65, 0.99) | 0.04 | 0.77 (0.62, 0.95) | 0.01 |
hPDI trajectories | ||||||||
Low and stable | 1677 | 25.7 | Reference | NA | Reference | NA | Reference | NA |
High and stable | 1176 | 18.4 | 0.75 (0.64, 0.89) | < 0.001 | 0.80 (0.67, 0.96) | 0.02 | 0.76 (0.64, 0.91) | 0.003 |
uPDI trajectories | ||||||||
Low and decreasing | 347 | 15.3 | Reference | NA | Reference | NA | Reference | NA |
High and decreasing | 1231 | 22.2 | 1.54 (1.15, 2.06) | 0.004 | 1.39 (1.03, 1.88) | 0.03 | 1.43 (1.06, 1.94) | 0.02 |
High and stable | 342 | 27.8 | 1.77 (1.26, 2.48) | < 0.001 | 1.70 (1.21, 2.38) | 0.002 | 1.77 (1.26, 2.49) | < 0.001 |
Low and increasing | 933 | 24.4 | 1.75 (1.30, 2.36) | < 0.001 | 1.61 (1.19, 2.18) | 0.002 | 1.72 (1.26, 2.33) | < 0.001 |