Fig. 6

Mendelian randomization analysis on the association between waist circumference and hypertension. AÂ Two sample Mendelian randomization analyses set waist circumference as exposure and hypertension as outcome. BÂ MR Egger, Weighted median, simple mode, and Inverse variance weighted models consistently indicated the genetical association between higher waist circumference and hypertension risk. CÂ The waist circumference and BMI were input collectively as exposures in the multivariable Mendelian randomization model. DÂ The Inverse variance weighted model showed that waist circumference was significantly associated with hypertension but not BMI