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Table 1 Information on 24 pleiotropic loci identified between 25OHD and MS

From: Association between 25(OH) vitamin D and multiple sclerosis: cohort, shared genetics, and Causality

Genomic Locus

Locus region

Lead SNP

P

symbol

PP.H4

1p36.32

1:2415191–2,756,397

rs4648390

7.83E-10

TTC34

0.045

1q21.3

1:150204405–151,246,241

rs11204708

1.45E-08

HORMAD1

0.357

1q25.2

1:178988598–179,807,727

rs3754133

7.93E-09

RP11-545A16.1

0.670

4q13.2

4:69509202–70,483,957

rs13123200

2.40E-08

UGT2B28, RP11-618I10.4

0.132

5p13.2

5:35649214–36,180,787

rs987106

4.19E-08

IL7R

0.185

6p24.3

6:6990747–7,328,165

rs4959426

4.26E-09

RREB1

0.967

6p22.2

6:25163549–26,594,542

rs1321247

1.40E-08

SCGN

0.954

6p22.1

6:28626101–29,614,419

rs3130248

1.86E-09

SUMO2P1

0.067

6p21.32

6:33179689–33,641,196

rs4484519

5.75E-13

ZBTB9, RN7SL26P

0.142

8q23.3

8:116464988–117,134,944

rs72681827

1.82E-09

LINC00536

0.212

10q23.33

10:93675891–94,791,270

rs7923837

3.48E-09

Y_RNA, EXOC6

0.479

11p15.2

11:13970901–15,126,262

rs3815984

7.61E-10

SPON1

0.335

11q23.3

11:116519358–117,144,194

rs5130

2.38E-08

APOC3

0.451

11q23.3

11:118459069–118,773,904

rs79504890

3.48E-08

RP11-158I9.1, SETP16

0.314

12q14.1

12:57634698–58,581,470

rs2069502

1.40E-13

CDK4

0.891

14q24.1

14:69138536–69,315,016

rs12435329

5.31E-09

RNU6-921P, ZFP36L1

0.286

14q32.33

14:103756160–104,537,680

rs2756119

3.78E-08

TRMT61A

0.663

16q23.2

16:79634279–79,656,673

rs6564681

4.62E-08

MAF, AC009159.1

0.575

17q12

17:34475471–35,008,350

rs3736166

4.48E-08

GGNBP2

0.533

17q21.32

17:45040389–46,646,427

rs11079784

1.37E-09

RP11-580I16.2

0.366

19p13.2

19:10633908–11,277,232

rs142158911

1.13E-13

SMARCA4, LDLR

0.956

19p13.11

19:18134596–18,409,068

rs62120396

1.22E-11

PDE4C

0.073

19q13.33

19:48322752–48,508,712

rs10405393

4.12E-08

BSPH1

0.308

20q13.2

20:52567414–52,820,687

rs6068816

3.98E-15

CYP24A1

0.000

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Nutrition Journal

ISSN: 1475-2891

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