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Table 3 Associations of ferritin and TSAT levels with risks for outcomes

From: Association of iron deficiency with kidney outcome and all-cause mortality in chronic kidney disease patients without anemia

 

Event/N (%)

Crude HR (95% CI)

P value

Adjusted HR (95% CI)

P value

Chronic kidney disease progression

    

Ferritin (ng/mL)

     

≤ 100

248/2,450 (10.1)

0.86 [0.74, 0.99]

0.035

1.11 [0.96, 1.29]

0.170

> 100

772/6,545 (11.8)

Reference

 

Reference

 

TSAT (%)

     

≤ 20

44/320 (13.8)

1.55 [1.12, 2.15]

0.009

1.66 [1.16, 2.37]

0.005

> 20

195/2,120 (9.2)

Reference

 

Reference

 

All-cause mortality

     

Ferritin (ng/mL)

     

≤ 100

432/4,398 (9.8)

0.86 [0.78, 0.96]

0.008

1.10 [0.99, 1.23]

0.087

> 100

1403/12,168 (11.5)

Reference

 

Reference

 

TSAT (%)

     

≤ 20

29/653 (4.4)

2.75 [1.79, 4.22]

< 0.001

2.21 [1.36, 3.57]

0.001

> 20

76/4,077 (1.9)

Reference

 

Reference

 
  1. Chronic kidney disease progression: adjusted for sex, age, eGFR, proteinuria, albumin, C-reactive protein, hemoglobin, total cholesterol, Charlson score, diabetes, hypertension, cardiovascular and cerebrovascular disease, liver disease, cancer, statins, and renin-angiotensin-aldosterone system inhibitor
  2. All-cause mortality: adjusted for sex, age, eGFR, proteinuria, albumin, C-reactive protein, hemoglobin, total cholesterol, Charlson score, diabetes, hypertension, cardiovascular and cerebrovascular disease, liver disease, and cancer