Combined 25-hydroxyvitamin D concentrations and physical activity on mortality in US stroke survivors: findings from the NHANES

Table 3 Joint association of PA and 25(OH)D with mortality in US Stroke survivors aged 70 years and younger, NHANES, 2007 to 2018

Mortality outcome	NLR	Adjusted model 1	P value	Adjusted model 2	P value	Adjusted model 3	P value
		HR (95%CI)		HR (95%CI)		HR (95%CI)
All causes
25(OH)D lower	No PA	1(Ref)		1(Ref)		1(Ref)
	PA	0.447(0.263,0.760)	0.003	0.375(0.229,0.616)	< 0.001	0.353(0.210,0.592)	< 0.001
25(OH)D higher	No PA	0.152(0.063,0.364)	< 0.001	0.190(0.078,0.463)	< 0.001	0.179(0.072,0.444)	< 0.001
	PA	0.154(0.050,0.473)	0.001	0.142(0.040,0.508)	0.003	0.132(0.038,0.460)	0.001
MACE
25(OH)D lower	No PA	1(Ref)		1(Ref)		1(Ref)
	PA	0.750(0.304,1.848)	0.531	0.765(0.278,2.102)	0.603	0.902(0.336,2.417)	0.837
25(OH)D higher	No PA	0.131 (0.025,0.690)	0.017	0.229(0.046,1.132)	0.071	0.246(0.052,1.167)	0.078
	PA	0.169(0.021,1.346)	0.093	0.282(0.029,2.792)	0.279	0.313(0.035,2.785)	0.297
Non-MACE
25(OH)D lower	No PA	1(Ref)		1(Ref)		1(Ref)
	PA	0.363(0.178,0.740)	0.005	0.284(0.149,0.541)	< 0.001	0.245(0.124,0.484)	< 0.001
25(OH)D higher	No PA	0.163(0.062,0.426)	< 0.001	0.178(0.060,0.532)	0.002	0.164(0.055,0.488)	0.001
	PA	0.152(0.040,0.578)	0.006	0.107(0.024,0.467)	0.003	0.092(0.023,0.363)	< 0.001

Model 1 adjusted for age and sex. Model 2 adjusted for age, sex, race, body mass index, education, history of smoking and drinking. Model 3 adjusted for age, sex, race, body mass index, education, history of smoking and drinking, and health factors (hypertension, dyslipidemia, diabetes, CVD)

ISSN: 1475-2891