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Table 1 Baseline characteristic of CAD patients with impaired kidney disease

From: Validation of the role of apolipoproteins in coronary artery disease patients with impaired kidney function for prognosis: a prospective cohort study in China

 

Overall

Non-MACE

MACE

P

n

1640

1316

324

 

Male (%)

670 (40.9)

531 (40.3)

139 (42.9)

0.439

Age, y

69.40 [62.88, 75.90]

69.10 [62.40, 75.60]

70.30 [64.88, 77.32]

0.005

BMI, kg/m2

25.70 [23.53, 27.73]

25.65 [23.59, 27.68]

25.95 [23.31, 27.95]

0.469

Clinical presentation

 ACS (%)

1116 (68.0)

876 (66.6)

240 (74.1)

0.011

 DM (%)

1040 (63.4)

793 (60.3)

247 (76.2)

 < 0.001

 Dyslipidemia (%)

1283 (78.2)

1029 (78.2)

254 (78.4)

0.996

 HBP (%)

1341 (81.8)

1079 (82.0)

262 (80.9)

0.696

 Family History CAD (%)

160 (9.8)

124 (9.4)

36 (11.1)

0.416

 Smoking (%)

858 (52.3)

689 (52.4)

169 (52.2)

0.999

Medications at discharge

 ARB.ACEI (%)

516 (31.5)

424 (32.2)

92 (28.4)

0.207

 CCB (%)

859 (52.4)

692 (52.6)

167 (51.5)

0.784

 NIT (%)

1572 (95.9)

1272 (96.7)

300 (92.6)

0.002

 beta (%)

1472 (89.8)

1179 (89.6)

293 (90.4)

0.73

 statin (%)

1613 (98.4)

1301 (98.9)

312 (96.3)

0.003

 Aspirin (%)

1624 (99.0)

1303 (99.0)

321 (99.1)

1

 Clopidogrel (%)

1619 (98.7)

1303 (99.0)

316 (97.5)

0.065

 Ticagrelor (%)

288 (17.6)

229 (17.4)

59 (18.2)

0.794

Laboratory data

 CR

1.36 [1.18, 1.52]

1.36 [1.18, 1.50]

1.41 [1.22, 1.58]

0.001

 eGFR, mL/min/1.73 m2

53.16 [46.58, 56.90]

53.42 [47.35, 57.03]

51.94 [41.45, 56.38]

 < 0.001

 HbA1C, %

6.50 [5.90, 7.50]

6.40 [5.90, 7.40]

6.80 [6.00, 8.00]

 < 0.001

 ApoA1, mmol/L

1.32 [1.14, 1.50]

1.34 [1.16, 1.51]

1.27 [1.11, 1.43]

 < 0.001

 ApoB, mmol/L

0.76 [0.63, 0.92]

0.76 [0.62, 0.91]

0.78 [0.64, 0.96]

0.06

 ApoB/ApoA1

0.58 [0.47, 0.72]

0.57 [0.46, 0.70]

0.61 [0.50, 0.78]

 < 0.001

 TC, mmol/L

3.96 [3.36, 4.74]

3.96 [3.36, 4.68]

4.02 [3.36, 4.98]

0.159

 TG, mmol/L

1.63 [1.21, 2.24]

1.63 [1.23, 2.21]

1.69 [1.17, 2.29]

0.805

 LDL, mmol/L

2.31 [1.82, 2.99]

2.30 [1.81, 2.95]

2.43 [1.85, 3.18]

0.08

 HDL, mmol/L

1.07 [0.89, 1.26]

1.08 [0.89, 1.26]

1.00 [0.87, 1.20]

0.003

 UA, mmol/L

406.88 [345.70, 484.60]

405.00 [343.37, 484.39]

416.28 [355.95, 487.52]

0.146

 HBG, g/dL

4.44 [4.03, 4.91]

4.48 [4.08, 4.92]

4.32 [3.84, 4.80]

 < 0.001

 PLT, K/uL

222.00 [182.00, 266.00]

222.50 [183.00, 268.00]

217.00 [181.75, 260.00]

0.185

 WBC, K/uL

6.95 [5.86, 8.34]

6.81 [5.77, 8.18]

7.40 [6.28, 9.02]

 < 0.001

Angiographic and PCI data

 Heavily calcified (%)

91 (5.5)

67 (5.1)

24 (7.4)

0.135

 LM (%)

73 (4.5)

61 (4.6)

12 (3.7)

0.563

 LAD (%)

643 (39.2)

520 (39.5)

123 (38.0)

0.654

 LCX (%)

244 (14.9)

206 (15.7)

38 (11.7)

0.091

 RCA (%)

642 (39.1)

502 (38.1)

140 (43.2)

0.108

 Syntax

13.00 [7.00, 20.50]

13.00 [7.00, 20.00]

14.00 [8.00, 22.00]

0.076

 MLD, mm

0.30 [0.04, 0.50]

0.30 [0.12, 0.50]

0.28 [0.00, 0.46]

0.002

 TIMI (%)

0

336 (20.5)

246 (18.7)

90 (27.8)

0.004

1

62 (3.8)

50 (3.8)

12 (3.7)

 

2

170 (10.4)

138 (10.5)

32 (9.9)

 

3

1072 (65.4)

882 (67.0)

190 (58.6)

 

 B2_C_lesion (%)

1218 (74.3)

956 (72.6)

262 (80.9)

0.003

 Lesion length, mm

25.00 [15.00, 39.00]

24.00 [15.00, 39.00]

26.00 [16.00, 40.00]

0.288

 Concentric (%)

264 (16.1)

219 (16.6)

45 (13.9)

0.261

 Stent length, mm

28.00 [18.00, 41.25]

29.00 [18.00, 42.00]

26.00 [18.00, 38.00]

0.01

 Stent (%)

1457 (88.8)

1184 (90.0)

273 (84.3)

0.005

  1. BMI Body mass index, WBC White blood cell, HBG Hemoglobin, PLT Platelet, eGFR Estimated glomerular filtration rate, ACS Acute coronary syndrome, DM Diabetes mellitus, PCI Percutaneous coronary intervention, TG Triglycerides, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, MLD Minimal lumen diameter, TIMI Thrombolysis In Myocardial Infarction, LM Left main coronary artery, RCA Right coronary artery, LAD Left anterior descending branch, LCX Left circumflex branch, SYNTAX Synergy between percutaneous coronary intervention with TAXUS and cardiac surgery