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Table 2 Biochemical indicators among the subjects in different groups

From: Epigenetic modifications of nuclear and mitochondrial DNA are associated with the disturbance of serum iron biomarkers among the metabolically unhealthy obesity school-age children

Indicators

Control group

(n = 65)

MHO group

(n = 60)

MUO group

(n = 44)

P

Glucose metabolism

    

 HbA1c (%)

5.02 ± 0.32

5.31 ± 0.27

5.48 ± 0.33*

0.047

 Fasting glucose (mM)

4.55 ± 0.21

4.99 ± 0.47

4.95 ± 0.40

0.817

 Fasting insulin (µIU/mL)

21.59 ± 5.15

27.91 ± 7.42

40.64 ± 8.21*#

0.008

 HOMA-β

854.13 ± 145.24

706.72 ± 108.52

565.22 ± 112.05*#

< 0.001

 HOMA-IR

5.09 ± 2.14

6.27 ± 2.33

9.12 ± 3.97*#

< 0.001

Lipid metabolism

    

 TG (mM)

1.03 ± 0.16

1.12 ± 0.28

1.36 ± 0.26*

0.043

 TC (mM)

4.02 ± 0.34

4.23 ± 0.62

4.71 ± 0.59*

0.031

 HDL-C (mM)

1.62 ± 0.13

1.32 ± 0.25

1.34 ± 0.37

0.542

 LDL-C (mM)

2.12 ± 0.34

2.43 ± 0.47

2.84 ± 0.18*

0.032

 VLDL-C (mM)

0.21 ± 0.0098

0.22 ± 0.13

0.27 ± 0.13

0.875

Liver function

    

 ALT (U/L)

16.25 ± 4.02

20.54 ± 3.78

52.46 ± 6.18*#

< 0.001

 AST (U/L)

19.05 ± 2.06

22.27 ± 3.06

37.71 ± 5.07*#

< 0.001

  1. Note All above variables were shown as mean ± standard deviation (SD) and analyzed by Bonferroni’s correction test after the one-way analysis of variance (ANOVA). MHO: metabolically healthy obesity, MUO: metabolically unhealthy obesity, HbA1c: glycosylated hemoglobin, HOMA-β: homeostasis model assessment of β cell function, HOMA-IR: homeostasis model assessment of insulin resistance, TG: triglyceride, TC: total cholesterol, HDL-C: high density lipoprotein cholesterol, LDL-C: low density lipoprotein cholesterol, VLDL-C: very low density lipoprotein cholesterol, ALT: alanine amino transferase, AST: aspartate transaminase. *Compared with the control group, P < 0.017, #Compared with the MHO group, P < 0.017