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Table 3 Interactions of meat intake with GRS for MAFLD

From: Meat and fish consumption, genetic risk and risk of severe metabolic-associated fatty liver disease: a prospective cohort of 487,875 individuals

 

Meat intake

 

GRS for MAFLD

 

Meat intake × GRS

βa

SE

P

 

βa

SE

P

 

βa

SE

P

Total meat

0.074

0.018

< 0.001

 

0.149

0.016

< 0.001

 

-0.002

0.018

0.928

Unprocessed red meat

0.067

0.015

< 0.001

 

0.147

0.016

< 0.001

 

0.016

0.015

0.275

Unprocessed poultry

0.058

0.016

< 0.001

 

0.149

0.016

< 0.001

 

0.003

0.016

0.857

Processed meat

0.025

0.016

0.131

 

0.150

0.016

< 0.001

 

-0.006

0.015

0.672

Oily fish

-0.008

0.016

0.617

 

0.148

0.016

< 0.001

 

-0.018

0.016

0.252

Non-oily fish

0.003

0.016

0.859

 

0.148

0.016

< 0.001

 

0.023

0.016

0.144

  1. CI confidence interval, GRS genetic risk score, MAFLD metabolic-associated fatty liver disease
  2. Cox proportional hazard regression models for MAFLD were performed using standardized values of meat intake and GRS
  3. aβ coefficients were adjusted for age, sex, ethnicity, centers, BMI, education, Household income, Townsend deprivation index, smoking, alcohol consumption, physical activity, energy, Alternate Mediterranean Diet score (total score minus the meat component), and other remaining meats