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Table 3 Adjusted hazard ratio (HR) and 95% confidence interval (CI) for all-cause mortality by the tertiles of common fatty acid intake among ovarian cancer patients

From: The association of dietary fat and fatty acid intake with ovarian cancer survival: findings from the OOPS, a prospective cohort study

Characteristics

All-cause mortality (N = 703)

Deaths (% of total)

HR (95% CI)

Capric acid (g/day)†

T1 (< 0.08)

34 (26.15)

1.00 (Ref)

T2 (0.08-< 0.13)

37 (28.46)

1.22 (0.74–1.99)

T3 (≥ 0.13)

59 (45.38)

1.92 (1.23-3.00)

P for trend *

 

< 0.05

Lauric acid (g/day)†

T1 (< 0.19)

37 (28.46)

1.00 (Ref)

T2 (0.19-< 0.30)

37 (28.46)

1.04 (0.65–1.68)

T3 (≥ 0.30)

56 (43.08)

1.49 (0.96–2.29)

P for trend *

 

< 0.05

Myristic acid (g/day)†

T1 (< 0.45)

32 (24.62)

1.00 (Ref)

T2 (0.45-< 0.70)

47 (36.15)

1.41 (0.87–2.28)

T3 (≥ 0.70)

51 (39.23)

1.86 (1.15–3.02)

P for trend *

 

< 0.05

Palmitic acid (g/day)†

T1 (< 5.30)

39 (30.00)

1.00 (Ref)

T2 (5.30-< 6.98)

35 (26.92)

1.03 (0.63–1.69)

T3 (≥ 6.98)

56 (43.08)

1.72 (1.07–2.76)

P for trend *

 

< 0.05

Stearic acid (g/day)†

T1 (< 1.42)

35 (26.92)

1.00 (Ref)

T2 (1.42-< 2.00)

45 (34.62)

1.78 (1.08–2.94)

T3 (≥ 2.00)

50 (38.46)

1.93 (1.12–3.31)

P for trend *

 

< 0.05

Arachidic acid (g/day)†

T1 (< 0.03)

44 (33.85)

1.00 (Ref)

T2 (0.03-< 0.05)

42 (32.31)

1.00 (0.62–1.63)

T3 (≥ 0.05)

44 (33.85)

1.25 (0.70–2.24)

P for trend *

 

0.41

Palmitoleic acid (g/day)†

T1 (< 0.36)

35 (26.92)

1.00 (Ref)

T2 (0.36-< 0.51)

49 (37.69)

1.66 (1.02–2.71)

T3 (≥ 0.51)

46 (35.38)

1.56 (0.89–2.74)

P for trend *

 

0.23

Oleic acid (g/day)†

T1 (< 6.99)

39 (30.00)

1.00 (Ref)

T2 (6.99-< 9.12)

40 (30.77)

1.27 (0.78–2.06)

T3 (≥ 9.12)

51 (39.23)

1.96 (1.13–3.40)

P for trend *

 

< 0.05

Erucic acid (g/day)†

T1 (< 0.10)

47 (36.15)

1.00 (Ref)

T2 (0.10-< 0.21)

28 (21.54)

0.54 (0.32–0.91)

T3 (≥ 0.21)

55 (42.31)

1.15 (0.75–1.77)

P for trend *

 

0.10

Linoleic acid (g/day)†

T1 (< 3.77)

45 (34.62)

1.00 (Ref)

T2 (3.77-< 4.97)

45 (34.62)

0.95 (0.60–1.52)

T3 (≥ 4.97)

40 (30.77)

1.15 (0.69–1.94)

P for trend *

 

0.56

α-linolenic acid (g/day)†

T1 (< 0.41)

45 (34.62)

1.00 (Ref)

T2 (0.41-< 0.57)

43 (33.08)

0.84 (0.52–1.34)

T3 (≥ 0.57)

42 (32.31)

1.06 (0.62–1.82)

P for trend *

 

0.69

Arachidonic acid (g/day)†

T1 (< 0.01)

41 (31.54)

1.00 (Ref)

T2 (0.01-< 0.02)

46 (35.38)

1.13 (0.71–1.79)

T3 (≥ 0.02)

43 (33.08)

0.93 (0.55–1.58)

P for trend *

 

0.73

Eicosapentaenoic acid (g/day)†

T1 (< 0.02)

38 (29.23)

1.00 (Ref)

T2 (0.02-< 0.04)

51 (39.23)

1.38 (0.86–2.20)

T3 (≥ 0.04)

41 (31.54)

1.05 (0.64–1.72)

P for trend *

 

0.87

Docosahexaenoic acid (g/day)†

T1 (< 0.01)

43 (33.08)

1.00 (Ref)

T2 (0.01-< 0.04)

45 (34.62)

1.05 (0.66–1.68)

T3 (≥ 0.04)

42 (32.31)

0.88 (0.55–1.42)

P for trend *

 

0.51

  1. CI, confidence interval; HR, hazard ratio; Ref, reference; T, tertile
  2. Values in bold indicate statistically significant results
  3. * HR and 95% CI were calculated through the Cox proportional hazards regression model with adjustment for age at diagnosis, education, smoking status, alcohol use, body mass index, physical activity, FIGO stage, histological type, histopathologic grade, menopausal status, parity, residual lesions, dietary change, total energy, total protein intake, and total carbohydrate intake
  4. † Adjusted for energy by the residual method
  5. * Test for trend based on variables containing the median value for each tertile