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Table 2 Contribution of body composition and abdominal fat distribution to glomerular filtration rate

From: Relationship between bmi and glomerular filtration rate in a large cohort initiating a weight loss program: differential contributions of fat mass, fat-free mass, and abdominal fat compartments

 

M1

M2

M3

M4

M5

M6

BMI (kg/m2)

−0.32***

0.05

    
 

[−0.39,−0.26]

[−0.03,0.12]

    

Body fat (%)

 

−0.59***

    
  

[−0.64,−0.53]

    

FMI (kg/m2)

  

−1.23***

−1.41***

−1.31***

−1.30***

   

[−1.35,−1.12]

[−1.55,−1.27]

[−1.44,−1.16]

[−1.43,−1.16]

FFMI (kg/m2)

  

0.79***

1.35***

1.42***

1.49***

   

[0.65,0.92]

[1.19,1.51]

[1.26,1.57]

[1.34,1.65]

VAT (cm)

   

−1.83***

−1.57***

−1.28***

    

[−2.00,−1.67]

[−1.75,−1.40]

[−1.45,−1.10]

SAT (cm)

   

3.21***

3.14***

3.01***

    

[2.86,3.57]

[2.78,3.50]

[2.66,3.36]

Metabolic syndrome (yes)

    

−4.33***

 
     

[−5.17,−3.50]

 

Impaired fasting glucose (yes)

     

−3.08***

      

[−3.80,−2.35]

High triglycerides (yes)

     

−1.73***

      

[−2.60,−0.86]

High blood pressure (yes)

     

−7.23***

      

[−7.92,−6.55]

Low HDL cholesterol (yes)

     

1.60***

      

[0.74,2.46]

Structured physical activity (≥ 2 h/w)

     

−2.55***

      

[−3.18,−1.93]

Constant

108.06***

118.59***

97.53***

89.81***

87.52***

89.22***

 

[106.11,110.02]

[116.43,120.75]

[95.35,99.70]

[87.47,92.16]

[85.15,89.89]

[86.90,91.54]

Observations

9704

9704

9704

9704

9704

9704

VIF

-

1.38

1.34

1.85

1.8

1.50

AIC

82,504

82,162

82,192

81,213

81,110

80,591

  1. Values are regression coefficients and 95% confidence intervals obtained from multivariable linear regression models
  2. M1: univariate: BMI (continuous)
  3. M2: multivariate: M1 + total body fat (continuous)
  4. M3: multivariate: FMI (continuous), FFMI (continuous)
  5. M4: multivariate: M3 + VAT (continuous), SAT (continuous)
  6. M5: multivariate: M4 + metabolic syndrome (discrete)
  7. M6: multivariate: M4 + impaired fasting glucose (discrete), high blood pressure (discrete), high triglycerides (discrete), low HDL-cholesterol (discrete) and physical activity (discrete)
  8. Abbreviations: FMI fat mass index, FFMI fat-free mass index, VAT visceral adipose tissue, SAT subcutaneous adipose tissue, VIF Variance Inflation Factor, AIC Akaike Information Criterion
  9. *p < 0.05
  10. **p < 0.01
  11. ***p < 0.001