Skip to main content

Table 3 Contribution of body composition and abdominal fat distribution to the risk of reduced glomerular filtration rate

From: Relationship between bmi and glomerular filtration rate in a large cohort initiating a weight loss program: differential contributions of fat mass, fat-free mass, and abdominal fat compartments

 

M1

M2

M3

M4

M5

M6

BMI (kg/m2)

1.02***

1.00

    
 

[1.01,1.03]

[0.99,1.01]

    

Body fat (%)

 

1.05***

    
  

[1.04,1.06]

    

FMI (kg/m2)

  

1.09***

1.12***

1.11***

1.11***

   

[1.07,1.11]

[1.10,1.14]

[1.09,1.13]

[1.09,1.13]

FFMI (kg/m2)

  

0.94***

0.90***

0.89***

0.88***

   

[0.93, 0.96]

[0.87,0.92]

[0.87,0.91]

[0.86,0.90]

VAT (cm)

   

1.17***

1.14***

1.11***

    

[1.14,1.20]

[1.11,1.17]

[1.09,1.14]

SAT (cm)

   

0.72***

0.73***

0.73***

    

[0.69,0.76]

[0.69,0.77]

[0.69,0.77]

Metabolic syndrome (yes)

    

1.52***

 
     

[1.35,1.70]

 

Impaired fasting glucose (yes)

     

1.31***

      

[1.18,1.46]

High triglycerides (yes)

     

1.15

      

[1.02,1.31]

High blood pressure (yes)

     

1.96***

      

[1.77,2.17]

Low HDL cholesterol (yes)

     

0.88

      

[0.78,1.00]

Structured physical activity (at least 2 h/w)

     

1.34***

      

[1.22,1.47]

Observations

9704

9704

9704

9704

9704

9704

VIF

-

1.26

1.24

1.71

1.69

1.71

AIC

11,716

11,614

11,628

11,211

11,262

10,960

  1. Values are odds ratios and 95% confidence intervals obtained from multivariable logistic regression models
  2. M1: univariate: BMI (continuous)
  3. M2: multivariate: M1 + total body fat (continuous)
  4. M3: multivariate: FMI (continuous), FFMI (continuous)
  5. M4: multivariate: M3 + VAT (continuous), SAT (continuous)
  6. M5: multivariate: M4 + metabolic syndrome (discrete)
  7. M6: multivariate: M4 + impaired fasting glucose (discrete), high blood pressure (discrete), high triglycerides (discrete), low HDL-cholesterol (discrete) and physical activity (discrete)
  8. Abbreviations: FMI fat mass index, FFMI fat-free mass index, VAT visceral adipose tissue, SAT subcutaneous adipose tissue, VIF Variance Inflation Factor, AIC Akaike Information Criterion
  9. *p < 0.05
  10. **p < 0.01
  11. ***p < 0.001